Francesco Ricci - University of Rome, Tor Vergata

Metrics (F. Ricci):
84 articles + 3 patents + 5 book chapters
h-index = 33
Citations: 3500 (source: Scopus, 8/2017: Scopus Author ID: 7103269464)


85. Ranallo S, Prévost-Tremblay C, Idili A, Vallée-Bélisle A, Ricci F (corr. author)
Antibody-powered nucleic acid release using a DNA-based nanomachine
Nature Commun 2017, 8, 15150. pdf
Featured in the following news media (C&ENE&T MagazineThe EngineerGEN, etc.)
Featured in the following Italian media (SkyTg24, Focus, ADNKronos, Galileo, etc.).
N°1 most read article of Nature Communications (May 2017).
84. Kuzyk A, Urban M, Idili A, Ricci F (co-corr. author), Liu N
Selective control of reconfigurable chiral plasmonic metamolecules
Science Advances 2017, 3, e1602803. pdf
Featured in the following news media (AzoNano,  ScienceDaily, PhysOrg, etc.).

83. Mariottini D, Idili A, Vallée-Bélisle A, Plaxco KW, Ricci F (corr. author)
A DNA Nanodevice that loads and releases a cargo with hemoglobin-like allosteric control and cooperativity
Nano Lett 2017, 17, 3225–3230. pdf 
82. Iacovelli F, Idili A, Benincasa A, Mariottini D, Ottaviani A, Falconi M, Ricci F (co- corr. author)Desideri A
Simulative and experimental characterization of a pH-dependent clamp-like DNA triple-helix nanoswitch
J Am Chem Soc 2017, 139, 5321-5329pdf  
81. Idili A, Ricci F (co-corr. author), Determining the folding and binding free energy of DNA-based nanodevices and nanoswitches using urea titration curves
Nucleic Acids Research 2017, in presspdf

80. Kwon E J, Skalak M, Bertucci A, Braun G, Ricci F, Ruoslahti E, Sailor M J, Bhatia S N
Porous Silicon Nanoparticle Delivery of Tandem Peptide Anti-Infectives for the Treatment of Pseudomonas aeruginosa Lung Infections

Adv Materials 2017, in press pdf
Featured in the following news media (EurekAlert,  ScienceNewsLine, PhysOrg, etc.).
Featured in Science Translational Medicine (Editor’s choice: Resistance is futile”)

79. Rossetti M, Ranallo S, Idili A, Palleschi G, Porchetta A, Ricci F (corr. author)
Allosteric DNA nanoswitches for controlled release of a molecular cargo triggered by biological inputs
Chem Science 2017, 8, 914-920. pdf
Featured in the Front Cover of Chemical Science
78. , , ,
Electrochemical DNA-Based Immunoassay That Employs Steric Hindrance To Detect Small Molecules Directly in Whole Blood
ACS Sensors 2017, in press. pdf
77. de Ávila BE, Zhao M, Campuzano S, Ricci F, Pingarrón JM, Mascini M, Wang J.
Rapid micromotor-based naked-eye immunoassay.
Talanta. 2017, 167, 651-657. pdf


TOC_V476. Amodio A, Adedeji A F, Castronovo M, Franco E, Ricci F (corr. author)
pH-controlled assembly of DNA tiles
J Am Chem Soc 2016, 138, 12735–12738. pdf 
toc_7375. Del Grosso E, Idili A, Porchetta A, Ricci F (corr. author)nanoscale_cover
A modular clamp-like mechanism to regulate the activity of nucleic-acid target-responsive nanoswitches with external activators
Nanoscale 2016, 8, 18057-18061. pdf
Featured in the Front Cover of Nanoscale 
74. Li H, Arroyo-Currás N, Kang D, Ricci F, Plaxco KWtoc_dual
Dual-reporter drift correction to enhance the performance of electrochemical aptamer-based sensors in whole blood
J Am Chem Soc 2016, 138, 15809–15812. pdf
TOC_7173. Ricci F,Vallée-Bélisle A, Simon A J, Porchetta A, Plaxco KW
Using Nature’s “Tricks” To Rationally Tune the Binding Properties of Biomolecular Receptors
Acc Chem Res 2016, 49, 1884–1892. pdf 
TOC_7272. Jeong H, Ranallo S, Rossetti M, Heo J, Shin J, Park K, Ricci F (co-corr. author), Hong J small_cover
Electronic Activation of a DNA Nanodevice Using a Multilayer Nanofilm
Small 2016,12, 40, 5572–5578. pdf
Featured in the Front Cover of Small  
TOC_7071. Della Sala F, Chen J, Ranallo S, Badocco D, Pastore P, Ricci F (co-corr. author), Prins L J
Reversible Electrochemical Modulation of a Catalytic Nanosystem
Angew Chem Int Ed 2016, 55 , 10737–10740. pdf 
TOC graphicChemical_Science_cover270. Ranallo S, Amodio A, Idili A, Porchetta A,  Ricci F (corr. author)
Electronic control of DNA-based nanoswitches and nanodevices
Chem Science 2016, 7, 66-71. pdf (open access)
Featured in the Front Cover of Chemical Science  
toc_69b69. ,, ,  Survey of Redox-Active Moieties for Application in Multiplexed Electrochemical Biosensors
Anal Chem 2016, 88, 10452–10458. pdf   


TOC6968. Del Grosso E, Dallaire A M,Vallée-Bélisle A,  Ricci F (corr. author)
Enzyme-Operated DNA-Based Nanodevices
Nano Lett 2015, 15, 8407–8411. pdf
67. Ranallo S, Rossetti M, Plaxco KW, Vallée-Bélisle A, Ricci F (corr. author)TOC67b
A Modular, DNA‐Based Beacon for Single‐Step Fluorescence Detection of Antibodies and Other Proteins
Angew Chem Int Ed 2015, 54, 13214–13218. pdf
Featured in the following news media (NDTV ScienceDaily, RAI-Radio3, etc.).
Access the recommendation on F1000Prime      
Article has an altmetric score of 219
TOC_6666. Mahshid SS, Camiré S, Ricci F, Vallée-Bélisle A
A highly selective electrochemical DNA-based sensor that employs steric hindrance effects to detect proteins directly in whole blood
J Am Chem Soc 2015, 137, 15596–15599. pdf
Featured in the following news media (CBC News ScienceDaily, etc.).
Article has an altmetric score of 148
TOC design_rev65. Idili A,  Porchetta A, Amodio A, Vallée-Bélisle ARicci F (corr. author)
Controlling Hybridization Chain Reactions with pH
Nano Lett 2015, 15, 5539–5544pdf
TOC-graphic64. Porchetta A,   Idili A,  Vallée-Bélisle ARicci F (corr. author)
A general strategy to introduce pH-induced allostery in DNA-based receptors to achieve controlled release of ligands
Nano Lett 2015, 15, 4467–4471. pdf (open access)
TOC6363. chemicalscience_coverAdornetto G,   Porchetta A,   Palleschi G,  Plaxco KW, Ricci F (corr. author)
A general approach to the design of allosteric, transcription-factor-regulated DNAzymes
Chem Science 2015, 6, 3692-3696. pdf
Featured in the Front Cover of Chemical Science  
TOC6462. Ren J, Hu Y, Lu C-H, Guo W, García MA, Ricci FWillner I
pH-Responsive and Switchable Triplex-Based DNA Hydrogels
Chem Science 2015, 6, 4190-4195. pdf


61. Amodio A, Bin Z, Porchetta A, Idili A, Castronovo M, Fan C, Ricci F (corr. author)TOC61
Rational Design of pH-Controlled DNA Strand Displacement
J Am Chem Soc 2014, 136, 16469–16472. pdf
60. Simon AJ,  Vallée-Bélisle A, Ricci F,  Plaxco KWTOC_60
Intrinsic disorder as a generalizable strategy for the rational design of highly responsive, allosterically cooperative receptors
Proc Natl Acad Sci U S A 2014, 111, 15048-15053.pdf
Featured in Science (Editor’s choice:
Disorder enhances binding cooperativity”)
59. Idili A, Vallée-Bélisle A, Ricci F (corr. author)TOC graphic
Programmable pH-triggered DNA nanoswitches
J Am Chem Soc 2014, 136, 5836–5839. pdf
Featured in the following news media (sciencedaily sciencenewsline, etc.).
58. Idili A, Amodio A, Vidonis M, Feinberg-Somerson J, Castronovo M, Ricci F (corr. author)
Folding-Upon-Binding and Signal-On Electrochemical DNA Sensor with High Affinity and SpecificityTOC_56
Anal Chem 2014, 86,  9013–9019. pdf
Featured in the cover page of Analytical Chemistry
 Among “most read articles” of Analytical Chemistry (August 2014)
TOC_5657. Puiu M, Idili A, Moscone D, Ricci F (co-corr. author), Bala C
A modular electrochemical peptide-based sensor for antibody detection 
Chem Comm 2014, 50, 8962-8965. pdf
TOC_5756.  Simon A, Vallée-Bélisle A, Ricci F, Watkins HM, Plaxco KW
Using the Population-Shift Mechanism to Rationally Introduce “Hill-type” Cooperativity into a Normally Non-Cooperative Receptor
Angew Chem Int Ed 2014, 53, 9471–9475. pdf
TOC_5555. Watkins HM, Simon A, Ricci F, Plaxco KW
Effects of Crowding on the Stability of a Surface-Tethered Biopolymer: An Experimental Study of Folding in a Highly Crowded Regime
J Am Chem Soc 2014, 136, 5836–5839. pdf


54. Idili A, Plaxco KW, Vallée-Bélisle A, Ricci F (corr. author)TOC_54
Thermodynamic Basis for Engineering High-Affinity, High-Specificity Binding-Induced DNA Clamp Nanoswitches
ACS Nano 2013, 7, 10863–10869. pdf
Featured in several news media (sciencedaily, montreal gazzette, gizmag, kuwaittimes, sciencenewsline, etc.).
53. Porchetta A, Vallée-Bélisle A, Plaxco KW, Ricci F (corr. author)TOC_24
Allosterically Tunable, DNA-Based Switches Triggered by Heavy Metals
J Am Chem Soc 2013, 135, 13238–13241. pdf
52. Esteban Fernández de Ávila B, Watkins HM, Pingarrón JM, Plaxco KW, Palleschi G, Ricci F (corr. author)TOC_23
Determinants of the Detection Limit and Specificity of Surface-Based Biosensors
Anal Chem 2013, 85, 6593–6597. pdf


TOC_751. Porchetta A, Vallée-Bélisle A, Plaxco KW, Ricci F (corr. author)
Using distal-site mutations and allosteric inhibition to tune, extend, and narrow the useful dynamic range of aptamer-based sensors.
J Am Chem Soc 2012, 134, 20601-4. pdf
Featured in  JACS Spotlight article and in many scientific news media (sciencedaily, biosciencetechnology, etc.). 
TOC_150. Vallée-Bélisle A, Ricci F (co-first author), Plaxco KW
Engineering biosensors with extended, narrowed, or arbitrarily edited dynamic range. 
J Am Chem Soc 2012, 134, 2876-9. pdf
Featured by Chemical & Engineering News, in JACS Spotlights (publications from JACS highlighted by the Editors), R&D magazine and in many scientific news media (sciencedaily, sciencenewsline, etc.). Versions of this story were also printed in: The Daily Nexsus, The bottom line,,
TOC_349. Vallée-Bélisle A, Ricci F (co-first author), Uzawa T, Xia F, Plaxco KW
Bioelectrochemical switches for the quantitative detection of antibodies directly in whole blood
J Am Chem Soc 2012, 134, 15197-200. pdf
Featured in ACS Chemical Biology Spotlight Articles 
Featured in many scientific news media (sciencedaily, sciencenewsline, etc.).
TOC_248. Ricci F, Vallée-Bélisle A, Porchetta A, Plaxco KW
Rational design of allosteric inhibitors and activators using the population-shift model: In vitro validation and application to an artificial biosensor
J Am Chem Soc 2012, 134, 15177-80. pdf
TOC_1247. Kang D, Vallée-Bélisle A, Porchetta A, Plaxco KW, Ricci F (corr. author)
Re-engineering electrochemical biosensors to narrow or extend their useful dynamic range
Angew Chemie Int Ed 2012, 51, 6717-21. pdf
TOC_646. Bonham AJ, Hsieh K, Ferguson BS, Vallée-Bélisle A, Ricci F, Soh HT, Plaxco KW
Quantification of transcription factor binding in cell extracts using an electrochemical, structure-switching biosensor
J Am Chem Soc 2012, 134, 3346-8. pdf
Microsoft Word - 3.doc45. Ricci F, Adornetto G, Palleschi G
A review of experimental aspects of electrochemical immunosensors
Electrochim Acta 2012, 84, 74-83. pdf
TOC_544. Watkins HM, Vallée-Bélisle A, Ricci F, Makarov DE, Plaxco KW
Entropic and electrostatic effects on the folding free energy of a surface-attached biomolecule: An experimental and theoretical study
J Am Chem Soc 2012, 134, 2120-6. pdf
TOC_1143. Rafael SP, Vallée-Bélisle A, Fabregas E, Plaxco K, Palleschi G, Ricci F (corr. author)
Employing the metabolic “branch point effect” to generate an all-or-none, digital-like response in enzymatic outputs and enzyme-based sensors
Anal Chem 2012, 84, 1076-82. pdf
TOC_1642. Biagiotti V, Porchetta A, Desiderati S, Plaxco KW, Palleschi G, Ricci F (corr. author)
Probe accessibility effects on the performance of electrochemical biosensors employing DNA monolayers
Anal  Bioanal Chem 2012, 402, 413-21. pdf


TOC_1741. Ricci F, Vallée-Bélisle A, Plaxco KW
High-precision, in vitro validation of the sequestration mechanism for generating ultrasensitive dose-response curves in regulatory networks
PLoS Comp Biol 2011, 7(10). pdf
TOC_440. Vallée-Bélisle A, Bonham AJ, Reich NO, Ricci F (corr. author), Plaxco KW
Transcription factor beacons for the quantitative detection of DNA binding activity
J Am Chem Soc 2011, 133, 13836-9. pdf
Featured by ACS PressPac (ACS PressPac contains reports of research selected from ACS journals and provides leads on the latest advances in science). Also featured in BioPhotonics (Photonics Media – Nov/Dec 2011, p.10) and in many scientific news media (sciencedaily, sciencenewsline, etc.).
39. Meneely JP, Ricci F, van Egmond HP, Elliott CT
Current methods of analysis for the determination of trichothecene mycotoxins in food
TrAC – Trends in Analytical Chemistry 2011, 30, 192-203. pdf


TOC_938 Patterson A, Caprio F, Vallée-Bélisle A, Moscone D, Plaxco KW, Palleschi G, Ricci F (corr. author)
Using triplex-forming oligonucleotide probes for the reagentless, electrochemical detection of double-stranded DNA
Anal Chem 2010, 82, 9109-15. pdf
Microsoft Word - Development of a recombinant Fab-fragment based37. Romanazzo D, Ricci F (corr. author), Volpe G, Elliott CT, Vesco S, Kroeger K, et al.
Development of a recombinant fab-fragment based electrochemical immunosensor for deoxynivalenol detection in food samples
Biosens Bioelectron 2010, 25, 2615-21. pdf
TOC_1336. Ricci F, Adornetto G, Moscone D, Plaxco KW, Palleschi G
Quantitative, reagentless, single-step electrochemical detection of anti-DNA antibodies directly in blood serum
Chem Comm 2010, 46, 1742-4. pdf
Featured by RSC Highlights


35. Ricci F, Pino F, Abagnale M, Messia MC, Marconi E, Volpe G, et al.
Direct electrochemical detection of trichothecenes in wheat samples using a 96-well electrochemical plate coupled with microwave hydrolysis
World Mycotoxin Journal 2009, 2, 239-45. pdf
TOC_834. Cash KJ, Ricci F, Plaxco KW.
A general electrochemical method for label-free screening of protein-small molecule interactions
Chem Comm 2009, 41, 6222-4. pdf
33. Romanazzo D, Ricci F (corr. author), Vesco S, Piermarini S, Volpe G, Moscone D, et al.
ELIME (enzyme linked immuno magnetic electrochemical) method for mycotoxin detection
J Visualized Experiments 2009(32). pdf
TOC_2132. Ricci F  (corr. author), Zari N, Caprio F, Recine S, Amine A, Moscone D, et al.
Surface chemistry effects on the performance of an electrochemical DNA sensor
Bioelectrochem 2009, 76, 208-13. pdf
TOC_2031. Vallée-Bélisle A, Ricci F, Plaxco KW
Thermodynamic basis for the optimization of binding-induced biomolecular switches and structure-switching biosensors.
Proc Natl Acad Sci U S A 2009, 106(33), 13802-7. pdf
TOC_1930.  Cash KJ, Ricci F, Plaxco KW
An electrochemical sensor for the detection of protein-small molecule interactions directly in serum and other complex matrices.
J Am Chem Soc
 2009, 131(20), 6955-7. pdf
TOC_1029. Ricci F, Bonham AJ, Mason AC, Reich NO, Plaxco KW
Reagentless, electrochemical approach for the specific detection of double- and single-stranded DNA binding proteins.
Anal Chem 2009, 81(4), 1608-14. pdf
28. Arduini F, Cassisi A, Amine A, Ricci F, Moscone D, Palleschi G
Electrocatalytic oxidation of thiocholine at chemically modified cobalt hexacyanoferrate screen-printed electrodes
J Electroanal Chem 2009, 626(1-2), 66-74. pdf


TOC_2227. Ricci F, Plaxco KW
E-DNA sensors for convenient, label-free electrochemical detection of hybridization
Microchimica Acta 2008, 163(3-4), 149-55. pdf
26. Ricci F, Moscone D, Palleschi G
Ex vivo continuous glucose monitoring with microdialysis technique: The example of GlucoDay
IEEE Sensors Journal 2008, 8(1), 63-70. pdf


25. Ricci F, Volpe G, Micheli L, Palleschi G
review on novel developments and applications of immunosensors in food analysis
Anal Chim Acta 2007, 605(2), 111-29. pdf
ISI Highly Cited Paper. In the top-ten most downloaded from Anal. Chim Acta in the period October-December 2007. Top-ten most cited paper in Anal. Chim. Acta in the period 2007-present.
24. Ricci F, Moscone D, Palleschi G
Procedure 17 preparation of prussian blue-modified screen-printed electrodes via a chemical deposition for mass production of stable hydrogen peroxide sensors 
Comprehensive Analytical Chemistry 2007, 49, e119-e124. Series edited by D- Barcelò (Elsevier) pdf
23. Ricci F, Moscone D, Palleschi G
Chapter 24 mediated enzyme screen-printed electrode probes for clinical, environmental and food analysis
Comprehensive Analytical Chemistry  2007, 49, 559-584. Series edited by D. Barceló (Elsevier) pdf
22. Ricci F, Lai RY, Plaxco KW
Linear, redox modified DNA probes as electrochemical DNA sensors
Chem Comm 2007(36), 3768-70. pdf
21. Arduini F, Amine A, Moscone D, Ricci F, Palleschi G
Fast, sensitive and cost-effective detection of nerve agents in the gas phase using a portable instrument and an electrochemical biosensor

Anal  Bioanal Chem 2007, 388(5-6), 1049-57. pdf
20. Ricci F, Lai RY, Heeger AJ, Plaxco KW, Sumner JJ
Effect of molecular crowding on the response of an electrochemical DNA sensor
Langmuir 2007, 23(12), 6827-34. pdf
19. Ricci F (corr. author), Caprio F, Poscia A, Valgimigli F, Messeri D, Lepori E, et al.
Toward continuous glucose monitoring with planar modified biosensors and microdialysis. study of temperature, oxygen dependence and in vivo experiment.
Biosens Bioelectron
 2007, 22(9-10), 2032-9. pdf
18. Ricci F (corr author), Amine A, Moscone D, Palleschi G
A probe for NADH and H2O2 amperometric detection at low applied potential for oxidase and dehydrogenase based biosensor applications
Biosens Bioelectron 2007, 22(6), 854-62. pdf
17. Piermarini S, Volpe G, Ricci F, Micheli L, Moscone D, Palleschi G, et al.
Rapid screening electrochemical methods for aflatoxin B1 and type-A trichothecenes: A preliminary study
Anal Lett 2007, 40(7), 1333-46. pdf


16. Arduini F, Ricci F (corr. author), Tuta CS, Moscone D, Amine A, Palleschi G
Detection of carbamic and organophosphorous pesticides in water samples using a cholinesterase biosensor based on prussian blue-modified screen-printed electrode.
Anal Chim Acta 2006, 580(2), 155-62. pdf
15. Ricci F (corr. author), Arduini F, Tuta CS, Sozzo U, Moscone D, Amine A, et al.
Glutathione amperometric detection based on a thiol-disulfide exchange reaction
Anal Chim Acta 2006, 558(1-2), 164-70. pdf


14. Arduini F, Ricci F, Bourais I, Amine A, Moscone D, Palleschi G
Extraction and detection of pesticides by cholinesterase inhibition in a two-phase system: A strategy to avoid heavy metal interference
Anal Lett 2005, 38(11), 1703-19. pdf
13. Suprun E, Evtugyn G, Budnikov H, Ricci F, Moscone D, Palleschi G
Acetylcholinesterase sensor based on screen-printed carbon electrode modified with prussian blue
Anal  Bioanal Chem 2005, 383(4), 597-604. pdf
12. Ricci F (corr. author), Palleschi G
Sensor and biosensor preparation, optimisation and applications of prussian blue modified electrodes
Biosens Bioelectron 2005, 21(3), 389-407. pdf
ISI Highly Cited Paper (Highly cited papers are papers that receive large amount of citations even long time after publication. The fraction is set to retrieve about 1% of top papers).  3rd most cited paper from Biosens. Bioelectron. in the period 2005-2010 and 7th  most cited paper in the last decade.  1st most downloaded in the period July-September 2005.
11. Poscia A, Messeri D, Moscone D, Ricci F, Valgimigli F.
A novel continuous subcutaneous lactate monitoring system
Biosens Bioelectron 2005, 20(11), 2244-50. pdf
10. Ricci F, Moscone D, Tuta CS, Palleschi G, Amine A, Poscia A, et al.
Novel planar glucose biosensors for continuous monitoring use
Biosens Bioelectron 2005, 20, 1993-2000. pdf
9. Arduini F, Ricci F, Palleschi G, Moscone D.
Modified Screen Printed Electrodes for glutathione detection
Sensors and Microsystems, Proceedings of the 9th Italian Conferences (2004), 61-66.


8. Ricci F, Palleschi G.
Report on the 3rd workshop of the european union concerted action-Evaluation/Validation of novel biosensors in real environmental and food samples, maó, menorca (balearic island), spain, november 2-4, 2003
Anal Lett 2004, 37(7), 1259-67.
7. Ricci F (corr. author), Arduini F, Amine A, Moscone D, Palleschi G
Characterisation of prussian blue modified screen-printed electrodes for thiol detection
J Electroanal Chem 2004, 563(2), 229-37. pdf
6. Ivanov A, Evtugyn G, Budnikov H, Ricci F, Moscone D, Palleschi G
Cholinesterase sensors based on screen-printed electrodes for detection of organophosphorus and carbamic pesticides
Anal  Bioanal Chem 2003, 377(4), 624-31. pdf
5. Ricci F (corr. author), Amine A, Moscone D, Palleschi G
Prussian blue modified carbon nanotube paste electrodes: A comparative study and a biochemical application
Anal Lett 2003, 36(9), 1921-38. pdf
4. Ricci F, Gonçalves C, Amine A, Gorton L, Palleschi G, Moscone D
Electroanalytical study of prussian blue modified glassy carbon paste electrodes
Electroanalysis 2003, 15(14), 1204-11. pdf
3. Ricci F, Amine A, Tuta CS, Ciucu AA, Lucarelli F, Palleschi G, et al.
Prussian blue and enzyme bulk-modified screen-printed electrodes for hydrogen peroxide and glucose determination with improved storage and operational stability
Anal Chim Acta 2003, 485(1), 111-20. pdf
2. Ricci F, Palleschi G, Yigzaw Y, Gorton L, Ruzgas T, Karyakin A
Investigation of the effect of different glassy carbon materials on the performance of prussian blue based sensors for hydrogen peroxide

Electroanalysis 2003, 15(3), 175-82. pdf
1. Ricci F, Amine A, Palleschi G, Moscone D
Prussian blue based screen printed biosensors with improved characteristics of long-term lifetime and pH stability
Biosens Bioelectron
 2003, 18(2-3), 165-74. pdf