Francesco Ricci - University of Rome, Tor Vergata

Francesco Ricci

Francesco Ricci – Associate professor
Principal Investigator

Curriculum Vitae
Francesco Ricci’s publications
Google Scholar profile


Alessandro Porchetta – post-doc researcher
I am studying switching based DNA biomolecules (molecular beacons, aptamers) for biosensing and drug release applications. I have recreated in-vitro nature’s tricks to both narrow and broaden the dynamic range of biological receptors that can undergo binding-induced conformational changes employing allosteric control (check my latest articles herehere and here).


Alessandro Bertucci – post-doc researcher
I am working on the possibility to use DNA-based nanodevices for cell imaging and drug-delivery applications. I am currently designing novel DNA-based nanodevices that can sense and respond upon binding to a specific transcription factor. Alessandro is currently a MSCA Global fellow with a project entitled “Multifunctional miRNA-targeting nanodevices for pluripotent cancer theranostics” (2017-2020). After a two-year period at UCSD he is currently based in our lab.

Andrea_IdiliAndrea Idili – post-doc researcher (past member)
My research  focuses on the understanding the thermodynamics of triplex DNA structure and how it can be used for the generation of new electrochemical (E-DNA) and optical DNA sensors. (check my latest articles here and here). Andrea is currently a post-doc researcher at the Plaxco lab at UCSB:


Alessia Amodio – post-doc researcher
The objective of my project is to develop and apply an easy-to-use, portable  sensor for the functional analysis and detection of tumour suppressor and oncogene proteins in tumour micro-samples with label-free, electrochemistry-based  devices. I am also studying novel methods to control the assembly and disassembly of DNA-based structures with pH. (check my latest articles here and here). Alessia is currently a MSCA Global fellow.


Simona Ranallo – PhD student (3rd year)
My research objective is to develop novel DNA-based optical nanoswitches for the detection of HIV-relevant antibodies. A paper about this project has recently been published in Angewandte Chemie (see here). I am also studying the possibility to activate and trigger DNA-based nanoswitches and nanomachines using electrochemical inputs. This last objective is relevant to our recent participation to the Biomod competition in 2014. Simona is currently a Veronesi Fellow.

EricaErica Del Grosso – PhD student (2nd year)
My research objective is to study novel strategies to trigger and activate DNA-based nanomachines and nanoswitches using enzymatic reactions. Currently I am also trying to adapt naturally occurring mechanisms to control and modulate the affinity of aptamers and DNA-based sensors.


DavideDavide Mariottini – PhD student (1st year)
My PhD project is aimed at recreating in the laboratory a hemoglobyn-like DNA nanomachine that can load and release a cargo in a cooperative way and that can be regulated with different allosteric cues.