Program
Pdf of the final program of the workshop here.
Posters’ list could be found below.
Click on the contribution’s title to get the pdf of the abstract.
Workshop program
19th June
9:00-10:00 Registration
10:15 Opening – Prof. Giuseppe Palleschi, president of the Analytical Chemistry Division of the Italian Chemical Society
10:30-12:30 Session #1 – Chair: Ido Bachelet
10:30-11:10 Kevin W. Plaxco (University of California, Santa Barbara) Stealing nature’s tricks to build better biosensors
11:10-11:50 Michael Famulok (Bonn University) Nanostructures based on interlocked DNA architectures
11:50-12:10 Matteo Castronovo (University of Udine) RNase H Self-Assembly Enables RNA Storage and Digital AFM Detection on a Highly Dense DNA Nanomatrix
12:10-12:30 Leila Motiei (Weizmann Institute) Targeted Protein Surface Sensors as a Tool for Analyzing Small Populations of Proteins in Biological Mixtures
12:30-14:00 Lunch
14:00-15:00 Session #2 – Chair: Shawn Douglas
14:00-14:20 Björn Högberg (Karolinska Institute) Spatial Control of Membrane Receptor Function using DNA-Origami Ligand Nano-Calipers
14:20-14:40 Christoph Wälti (University of Leeds) Introducing functionality site-specifically into DNA nanomaterials
14:40-15:00 Alessandro Porchetta (University of Rome, Tor Vergata) Using triplex DNA to achieve pH-control over reactions
15:00-15:40 Session #3 – Chair: Tambet Teesalu
Poster Flash Presentation (5 minutes each)
15:40-16:50 Coffee Break + Poster session
16:50-18:30 Session #4 – Chair: Tim Liedl
16:50-17:30 Shawn Douglas (University of California, San Francisco) Nanoscale Construction with DNA
17:30-17:50 Alessandro Desideri (University of Rome, Tor Vergata) A truncated DNAoctahedral cage and geometrical variations to control proteins trappping and release
17:50-18:10 Aleksei Aksimentiev (University of Illinois at Urbana-Champaign) Predicting the Transport Properties of DNA Origami Objects through All-Atom Molecular Dynamics Simulations
18:10-18:30 Piero Morales (ENEA Research Center) Selfassemblage of DNA origamis on inorganic nanodots
20:30/21:00 Social Dinner
20th June
9:15-10:35 Session #5 – Chair: Kevin W. Plaxco
9:15-9:55 Ebbe Sloth Andersen (Aarhus University) DNA and RNA origami design
9:55-10:15 Cosimo Ducani (Karolinska Institute) Enzymatic production of ‘monoclonal stoichiometric’ single stranded DNA oligonucleotides
10:15-10:35 Luca Piantanida (IOM-CNR) Monitoring DNA origami actuation with a plasmon ruler
10:35-11:00 Session #6 – Chair: Giuseppe Palleschi
Poster Flash Presentation (5 minutes each)
11:00-12:00 Coffee Break + poster
12:00-13:20 Session #7 – Chair: Ebbe Sloth Andersen
12:00-12:40 Tambet Teesalu (Sanford-Burnham Medical Research Institute) Tumor penetrating peptides
12:40-13:00 Sara Tombelli (CNR) Molecular beacons and PMMA nanoparticles for the detection and silencing of mRNA in human cancer cells
13:00-13:20 Mette D.E. Jepsen (Aarhus University) Constructing fuzzy and Boolean logic gates in DNA
13:20-15:20 Lunch
15:20-16:50 Session #8 – Chair: Francesco Ricci
15:20-15:40 Giampaolo Zuccheri (University of Bologna) DNA Nanostructures assembly and potential use as intracellular biosensors in single live human cells
15:40-16:00 Nicola Borbone (University of Naples) Anti HIV activity of monomolecular tetra-end-linked analogues of the SA-1042 aptamer targeted against the viral envelope glycoprotein gp120
16:00-16:20 Christopher O’Kane (Ulster University) Enhanced Intrinsic Fluorescence of Rationally Designed G-wire Assemblies
16:20-16:40 Giuseppe Arrabito (Dortmund University) Multiplexed Sub-Cellular Scale Microarrays from direct DNA Nanolithography
16:40 Closing remarks
Poster Program
P-1 DNAzyme switching probes for the quantitative detection of transcription factors
G. Adornetto, A. Porchetta, G. Palleschi, K.W. Plaxco, F. Ricci
P-2 Folding-upon-binding and signal-on electrochemical DNA sensor with high affinity and specificity
A. Amodio, A. Idili,J. Feinberg-Somerson, M. Castronovo, F. Ricci
P-3 Electrochemical Affinity Biosensors for the Detection of Tumor Necrosis Factor alpha
F. Bettazzi, D. Voccia, I. Palchetti
P-4 Cell proliferation assay: EdU an alternative to BrdU
V. Cassinelli, B. Oberleitner, A. Manetto and T. Frischmuth
P-5 Delivery and imaging of miRNAs-mimicking oligonucleotides by multifunctional carbon nanotubes. Innovative therapeutic tools for biomedical applications
A. Celluzzi, A. Caporali, S. Bellucci, and A. Masotti
P-6 Enzyme Reactivity of DNA Origami
L. Coral, A. Stopar, D. Chang, and M. Castronovo
P-7 Experimental Assembly and Simulative Analysis of an Entirely Double-Stranded Octahedral DNA-cage
F. Iacovelli, M. Falconi, S. Juul, B.R. Knudsen and A. Desideri
P-8 Programmable pH-Triggered DNA Nanoswitches
A. Idili, A. Vallée-Bélisle, F. Ricci
P-9 Label-free luminescent switch-on detection of endonuclease IV activity using a G-quadruplex-selective iridium(III) complex
K.H. Leung, H.Z. He, W. Wang, H.J. Zhong, D.S.H Chan, C.H. Leung and D.L. Ma
P-10 New electrochemical peptide sensor for antibodies detection
M. Puiu, F. Ricci,C. Bala and D. Moscone
P-11 Chemical stability studies of mesoporous oxidized silicon for the synthesis of mixed-sequence oligonuclotides
F. Nici, M. Terracciano, N. Borbone, L. De Stefano, S. D’Errico, G. Piccialli, I. Rea, G. Oliviero
P-12 Synthesis of new anti-HIV aptamers based on tetra-end-linked DNA G-quadruplexes and investigation of the effect of the base sequence on anti-HIV activity
B. Pinto, F. Nici, V. D’Atri, G. Oliviero, S. D’Errico, L. Mayol, V. Piccialli, S. Haider, B. Hoorelbeke, J. Balzarini, and N. Borbone
P-13 Nature-inspired DNA nanoswitches for antibodies detection
S. Ranallo, A. Valleè-Belisle, K.W. Plaxco, F. Ricci
P-14 A novel DNA-aptamer based array for pesticide detection
R. Rapini, G. Aydoğdu, G. Marrazza
P-15 The high resolution crystal structure of an all modified LNA G-quadruplex: a compact moiety with potential application in nanotechnology
I. Russo Krauss, G. Parkinson, A. Merlino, A. Randazzo,E. Novellino, C.A. Mattia, L. Mazzarella, F. Sica
P-16 Patterning DNA scaffolds with 3 nm long RecA nucleoprotein protein filaments
R. Sharma, A.G. Davies, C. Wälti
P-17 Structural motifs that govern the recognition process between thrombin and aptamers
I. Russo Krauss, A. Pica, A. Merlino, L. Mazzarella, F. Sica
P-18 DNA-based nanocontainers for predesigned spatial confinement of proteins
A. Sprengel, M. Merdanovic, M. Ehrmann and B. Saccà
P-19 DNA Origami as Matrices for Enzyme imprinting
A. Stopar, L. Coral, S. Di Giacomo, and M. Castronovo
P-20 DNA Origami Nanorobot with a Controlled Flap
E. Torelli, M. Marini,S. Palmano, L. Piantanida, C. Polano, A. Scarpellini, M. Lazzarino, G. Firrao
P-21 New Capture-SELEX approach for label-free small drug detection in human serum
Fabio M. Spiga, Anna Ferretti, Carlotta Guiducci